Doral - Sleep Aid and Insomnia Treatment

Questcor - Doral - Sleep Aid for Insomnia Treatment
  Doral is the only benzodiazepine that is  
Uniquely BZ1 selective1

Doral® acts selectively on the BZ1 receptor—unlike conventional benzodiazepines.1 BZ1 receptor selectivity permits effective hypnosis, while reducing side effects, including tolerance, common to nonselective benzodiazepines.1

  • Doral is the only available benzodiazepine selective for the BZ1 receptor1
  • BZ1 receptor selectivity offers the benefits of a hypnotic agent without many of the drawbacks of typical benzodiazepines1
  • Doral binds preferentially to BZ1 receptors in the pons and lamina IV—regions that may be involved in the primary and secondary mechanisms of sedation and sleep2

Doral is a hypnotic benzodiazepine with a unique pharmacological profile2

References: 1. Kales A. Quazepam: hypnotic efficacy and side effects. Pharmacotherapy. 1990;10;(1):1-12. 2. Hilbert JM, Battista D. Quazepam and flurazepam: differential pharmacokinetic and pharmacodynamic characteristics. J Clin Psychiatry. 1991;52(suppl 9):21-26.